Brassinosteroids Rescue the Deficiency of CYP90, a Cytochrome P450, Controlling Cell Elongation and De-etiolation in Arabidopsis

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Brassinosteroids Rescue the Deficiency of CYP90, a Cytochrome P450, Controlling Cell Elongation and De-etiolation in Arabidopsis

The cpd mutation localized by T-DNA tagging on Arabidopsis chromosome 5-14.3 inhibits cell elongation controlled by the ecdysone-like brassinosteroid hormone brassinolide. The cpd mutant displays de-etiolation and derepression of light-induced genes in the dark, as well as dwarfism, male sterility, and activation of stress-regulated genes in the light. The CPD gene encodes a cytochrome P450 (CY...

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Patients with congenital adrenal hyperplasia, exhibiting combined CYP17 and CYP21 deficiency, were shown by Arlt et al. (2004) to harbor a 541T-->G mutation in exon 5 of POR (encoding NADPH-cytochrome P450 reductase, CYPOR), which resulted in a Y181D substitution that obliterated electron transfer capacity. Using bacterial expression models, we examined catalytic and physical properties of the ...

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15 صفحه اول

Activation of the cytochrome P450 gene, CYP72C1, reduces the levels of active brassinosteroids in vivo.

A pool of Arabidopsis lines transformed with the activation vector was screened for short hypocotyl mutants under dim far-red light, and three mutant lines designated chibi1-3 (chi) were isolated. Among the chi mutants, chi2 was dominant. The chi2 seedlings were short, regardless of the light conditions. The chi2 mature plants exhibited phenotypic features such as dwarfism, reduced male fertili...

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ژورنال

عنوان ژورنال: Cell

سال: 1996

ISSN: 0092-8674

DOI: 10.1016/s0092-8674(00)81094-6